Image Analysis based Companion Diagnostics (CDx) on Leica’s Aperio ePathology platform

Flagship Biosciences’ custom image analysis development leverages Leica Biosystems’ strong installed base in digital pathology Boulder, CO – April 30, 2014 – Flagship Biosciences announces it has reached agreement with Leica Biosystems to allow its custom algorithms to be utilized in companion diagnostics development on the Aperio ePathology platform. The agreement allows Flagship’s quantitative analysis […]

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Flagship appoints new Head of Biology

Boulder, CO – April 3 2014 – Flagship Biosciences announced that Dr. Anthony J. Milici has been appointed Head of Biology. Dr. Milici brings over 30 years of pharmaceutical drug development experience in the areas of neurodegenerative disease, inflammation, and oncology. Prior to joining Flagship, Dr. Milici was head of a neuroscience imaging lab with […]

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Quantitative diagnostic antibody drug conjugate presentation

Flagship Biosciences presents quantitative diagnostic antibody development process at Protein Science Week Palm Springs, CA – Jan. 14, 2014 – Flagship presented an in-depth look at companion diagnostic development at Protein Science Week. The presentation, Immunohistochemistry Based Companion Diagnostic Strategies for Antibody Drug Conjugates, covered Flagship Bioscience’s novel approach to developing assays and biomarkers in […]

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Enzo and Flagship advance in situ hybridization CDx

Enzo Biochem and Flagship Biosciences partner to provide tissue-based companion diagnostics offering complete solution for in situ hybridization development to pharmaceutical companies New York, NY – December 11, 2013 – Enzo Biochem Inc. (NYSE:ENZ) and Flagship Biosciences LLC, of Boulder, CO, today announced a partnership in tissue-based companion diagnostics that will enable personalized diagnosis and treatment […]

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Flagship Biosciences presents immunology image analysis validation research

Validation of an Image Analysis Algorithm to Quantify Leukocyte Populations Using Whole Slide Digital Image Analysis poster presented at SITC National Harbor, MD – Nov. 7, 2013 – Abstract- In recent years, the tumor microenvironment (TME) has been identified as an important factor influencing the growth and metastasis of the tumor. In the TME, different classes […]

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Article published using AngioMap for evaluating microvessel density in multiple myeloma

Flagship and University of Utah publish article on evaluating the plasma cell distribution with the bone marrow vascular niche Boulder, CO – Sept. 16 2013 – In multiple myeloma, bone marrow angiogenesis is typically increased and microvessel density (MVD) is a known indicator of poor prognosis. The technical difficulties associated with consistently measuring three dimensional […]

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Flagship Boulder location undamaged by flood

Boulder, CO – 17 – Sept. – 2013 – A torrential 100 year flood left nearby towns and much of the foothills west of Boulder, Colorado damaged or inaccessible this week, as a massive stormed dumped almost 16″ of rain over a few days. The Flagship team was largely unaffected by the storm and flooding, […]

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The quantitative nature of digital pathology requires integrated biostatistics services

Rapid changes in the pharmaceutical industry and in the discipline of pathology expand the need for biostatistics Boulder, CO — July 29, 2013 — Flagship Biosciences, a leading provider of tissue analysis for pharmaceutical and medical device development, has added biostatistics services for preclinical and clinical trials support. A complete service in tissue analysis requires […]

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Mile High Histology

Correcting histology protocols designed for lower elevations in high altitude laboratories Heat induced epitope retrieval (HIER) and enzyme induced epitope retrieval (EIER) are used to unmask proteins which have been cross linked by aldehyde fixatives on slide-mounted tissues that have been formalin fixed and paraffin embedded (FFPE).  Cross linking of proteins with aldehyde fixatives preserves […]

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Antibody Selection

Primary and secondary antibody selection for immunohistochemistry. Selecting a primary and secondary antibody can present a number of challenges.  In order to help immunohistochemistry labs make this selection process easier, presented here are tips from experts in the field.  There are a number of considerations and concerns in antibody selection, some of which are covered […]

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