Quantitative diagnostic antibody drug conjugate presentation

Flagship Biosciences presents quantitative diagnostic antibody development process at Protein Science Week Palm Springs, CA – Jan. 14, 2014 – Flagship presented an in-depth look at companion diagnostic development at Protein Science Week. The presentation, Immunohistochemistry Based Companion Diagnostic Strategies for Antibody Drug Conjugates, covered Flagship Bioscience’s novel approach to developing assays and biomarkers in […]

Read More

Enzo and Flagship advance in situ hybridization CDx

Enzo Biochem and Flagship Biosciences partner to provide tissue-based companion diagnostics offering complete solution for in situ hybridization development to pharmaceutical companies New York, NY – December 11, 2013 – Enzo Biochem Inc. (NYSE:ENZ) and Flagship Biosciences LLC, of Boulder, CO, today announced a partnership in tissue-based companion diagnostics that will enable personalized diagnosis and treatment […]

Read More

Flagship Biosciences presents immunology image analysis validation research

Validation of an Image Analysis Algorithm to Quantify Leukocyte Populations Using Whole Slide Digital Image Analysis poster presented at SITC National Harbor, MD – Nov. 7, 2013 – Abstract- In recent years, the tumor microenvironment (TME) has been identified as an important factor influencing the growth and metastasis of the tumor. In the TME, different classes […]

Read More

Article published using AngioMap for evaluating microvessel density in multiple myeloma

Flagship and University of Utah publish article on evaluating the plasma cell distribution with the bone marrow vascular niche Boulder, CO – Sept. 16 2013 – In multiple myeloma, bone marrow angiogenesis is typically increased and microvessel density (MVD) is a known indicator of poor prognosis. The technical difficulties associated with consistently measuring three dimensional […]

Read More

Flagship Boulder location undamaged by flood

Boulder, CO – 17 – Sept. – 2013 – A torrential 100 year flood left nearby towns and much of the foothills west of Boulder, Colorado damaged or inaccessible this week, as a massive stormed dumped almost 16″ of rain over a few days. The Flagship team was largely unaffected by the storm and flooding, […]

Read More

The quantitative nature of digital pathology requires integrated biostatistics services

Rapid changes in the pharmaceutical industry and in the discipline of pathology expand the need for biostatistics Boulder, CO — July 29, 2013 — Flagship Biosciences, a leading provider of tissue analysis for pharmaceutical and medical device development, has added biostatistics services for preclinical and clinical trials support. A complete service in tissue analysis requires […]

Read More

Mile High Histology

Correcting histology protocols designed for lower elevations in high altitude laboratories Heat induced epitope retrieval (HIER) and enzyme induced epitope retrieval (EIER) are used to unmask proteins which have been cross linked by aldehyde fixatives on slide-mounted tissues that have been formalin fixed and paraffin embedded (FFPE).  Cross linking of proteins with aldehyde fixatives preserves […]

Read More

Antibody Selection

Primary and secondary antibody selection for immunohistochemistry. Selecting a primary and secondary antibody can present a number of challenges.  In order to help immunohistochemistry labs make this selection process easier, presented here are tips from experts in the field.  There are a number of considerations and concerns in antibody selection, some of which are covered […]

Read More

Flagship Biosciences develops quantitative pathology analysis of fibrosis

Presentation at the Society for Toxicologic Pathology demonstrates quantitative analysis of fibrosis in nonalcoholic steatohepatitis. 18 June 2013  Portland, OR. Flagship Biosciences presented  “Image Analysis Quantification of Liver Fibrosis in Animal Models of Nonalcoholic Steatohepatitis (NASH)” at the Society for Toxicologic Pathology. Nonalcoholic steatohepatisis or NASH is a common, often “silent” chronic liver disease, occurring […]

Read More

Flagship Biosciences Evaluating Her2 RNA and Protein Expression

Recent Flagship Biosciences developments for evaluating Her2 with image analysis tools was presented at the annual AACR conference. The research received some attention from Genetic Engineering & Biotechnology News.  In their May 15, 2013 (Vol. 33 No. 10) issue feature article, “Cancer Diagnostics, Pushing the Boundaries,” Vicki Glaser expands upon Flagship Biosciences’ use of the […]

Read More