Publications

Richardson F, Young GD, Sennello R, Wolf J, Argast GM, Mercado P, Davies A, Epstein DM, Wacker B. The evaluation of E-Cadherin and vimentin as biomarkers of clinical outcomes among patients with non-small cell lung cancer treated with erlotinib as second- or third-line therapy.Anticancer Res. 2012 Feb;32(2):537-52.

Scott L, Feng J, Kiss T, Needle E, Atchison K, Kawabe TT, Milici AJ, Hajós-Korcsok E, Riddell D, Hajós M. Age-dependent disruption in hippocampal theta oscillation in amyloid-β overproducing transgenic mice. Neurobiol Aging. 2012 Jul;33(7):1481

La Porte SL, Bollini SS, Lanz TA, Abdiche YN, Rusnak AS, Ho WH, Kobayashi D, Harrabi O, Pappas D, Mina EW, Milici AJ, Kawabe TT, Bales K, Lin JC, Pons J. Structural basis of C-terminal β-amyloid peptide binding by the antibody ponezumab for the treatment of Alzheimer’s disease. J Mol Biol. 2012 Aug 24;421(4-5):525-36

Samaroo HD, Opsahl AC, Schreiber J, O’Neill SM, Marconi M, Qian J, Carvajal-Gonzalez S, Tate B, Milici AJ, Bales KR, Stephenson DT. High throughput object-based image analysis of β-amyloid plaques in human and transgenic mouse brain. J Neurosci Methods. 2012 Feb 15;204(1):179-88.

Potts SJ, Huff SE, Lange H, Zakharov V, Eberhard DA, Krueger JS, Hicks DG, Young GD, Johnson T, Whitney-Miller CL. Tissue Pattern Recognition Error Rates and Tumor Heterogeneity in Gastric Cancer.Appl Immunohistochem Mol Morphol. 2012

Potts SJ, Krueger JS, Landis ND, Eberhard DA, David Young G, Schmechel SC, Lange H. Evaluating tumor heterogeneity in immunohistochemistry-stained breast cancer tissue. Lab Invest. 2012 Sep;92(9):1342-57

Argast GM, Krueger JS, Thomson S, Sujka-Kwok I, Carey K, Silva S, O’Connor M, Mercado P, Mulford IJ, Young GD, Sennello R, Wild R, Pachter JA, Kan JL, Haley J, Rosenfeld-Franklin M, Epstein DM. Inducible expression of TGFβ, snail and Zeb1 recapitulates EMT in vitro and in vivo in a NSCLC model. Clin Exp Metastasis. 2011 Oct;28(7):593-614.

Kiss T, Hoffmann WE, Scott L, Kawabe TT, Milici AJ, Nilsen EA, Hajós M. Role of Thalamic Projection in NMDA Receptor-Induced Disruption of Cortical Slow Oscillation and Short-Term Plasticity. Front Psychiatry. 2011 Apr 4;2:14.

Potts, SJ, Johnson, TD, Voelker, FA, Lange, H, Young, GD. Multiplexed Measurement of Proteins in Tissue in a Clinical Environment. Appl Immun Mol Morph. 2011 – 19(6):494–498

Lange, H. Digital pathology: A regulatory overview. Lab Medicine 2011 42:587-591.

Nassar, A, Cohen, C, Albitar, M, Agersborg, S, Zhou, W, Lynch, K, Heyman, E, Lange, H, Siddiqui, MT. Reading Immunohistochemical Slides on a Computer Monitor—A Multisite Performance Study Using 180 HER2-stained Breast Carcinomas. Appl Immun Mol Morph 2011 19(3):212–217.

Aziza Nassar, Cynthia Cohen, Sally S. Agersborg, Weidong Zhou, Kathleen A. Lynch, Maher Albitar, Edward A. Barker, Burton L. Vanderbilt, Jim Thompson, Eugene R. Heyman, Holger Lange, Allen Olson, and Momin T. Siddiqui. Trainable Immunohistochemical HER2/neu Image Analysis: A Multisite Performance Study Using 260 Breast Tissue Specimens. Arch Path Lab Med 2011 135(7):896-902.

Nassar, A, Cohen, C, Agersborg, S, Zhou, W, Lynch, K, Heyman, E, Olson, A, Lange, H, Siddiqui, MT. A New Immunohistochemical ER/PR Image Analysis System: A Multisite Performance Study. Appl Immun Mol Morph 2011 19(3):195-202.

Duttaroy A, Voelker F, Merriam K, Zhang X, Ren X, Subramanian K, Hughes TE, Burkey BF. The DPP-4 inhibitor vildagliptin increases pancreatic beta cell mass in neonatal rats. Eur J Pharmacol. 2011 Jan 15;650(2-3):703-7.

Mihaela Lorger, Joseph S. Krueger, Melissa O’Neal, Karin Staflin, and Brunhilde Felding-Habermann. Activation of tumor cell integrin v3 controls angiogenesis and metastatic growth in the brain. PNAS. 2009 106(26):10666-10671

Potts SJ, Young GD, Voelker FA. The role and impact of quantitative discovery pathology. Drug Discov Today. 2010 Nov;15(21-22):943-50.

Staflin K, Krueger JS, Hachmann J, Forsyth JS, Lorger M, Steiniger SC, Mee J, Pop C, Salvesen GS, Janda KD, Felding-Habermann B. Targeting activated integrin alphavbeta3 with patient-derived antibodies impacts late-stage multiorgan metastasis. Clin Exp Metastasis. 2010 Apr;27(4):217-31

Kellar, RS, Hubka, M, Rheins, LA, Fisher, G, Naughton, GK. Hypoxic Conditioned Culture Medium From Fibroblasts Grown Under Embryonic-like Conditions Supports Healing Following Post-laser Resurfacing. Journal of Cosmetic Dermatology. 8(3):190-196. 2009

Thai, HM. Juneman, E, Castellano, L, Do, R, Hagerty, T, Lancaster, J, Kellar, RS, Williams, S, Sethi, G, Schmelz, M, Gaballa, M, and Goldman, S. Implantation of a 3 dimensional fibroblast matrix improves left ventricular function and blood flow after acute myocardial infarction. Cell Transplantation. April 10. pii: CT-1921. 2009.

Potts SJ. Digital pathology in drug discovery and development: multisite integration. Drug Discov Today. 2009 Oct;14(19-20):935-41.

Safety and Efficacy of an Shigella flexneri 2a icsA-iuc Attenuated Vaccine in Rhesus Monkeys.  Echeverra, P. MacMillan, J, Young, G.D., Hanchalay, S., Ngampochjana, M., Pitarangsi, C. Fontaine, A. Sansonetti, P., Oaks, E.V., Hale, T.L.; (accepted for publication).

Naughton, GK and Kellar, RS. Human Extracellular Matrix for Medical Devices and Therapeutics. Medical Device and Diagnostic Industry. May 2008.

Geurs, N, Korostoff, JM, Kang, TH, Jeffcoat, M, Kellar, RS, Reddy, M. Clinical and Histologic Assessment of Lateral Alveolar Ridge Augmentation Using a Synthetic Long-Term Bioabsorbable Membrane and an Allograft Journal of Periodontology. 79:1133-1140, 2008.

Chen EI, Hewel J, Krueger JS, Tiraby C, Weber MR, Kralli A, Becker K, Yates JR 3rd, Felding-Habermann B. Adaptation of energy metabolism in breast cancer brain metastases. Cancer Res. 2007 Feb 15;67(4):1472-86.

Buck E, Eyzaguirre A, Barr S, Thompson S, Sennello R, Young D, Iwata KK, Gibson NW, Cagnoni P, Haley JD. Loss of homotypic cell adhesion by epithelial-mesenchymal transition or mutation limits sensitivity to epidermal growth factor receptor inhibition. Mol Cancer Ther. 2007 Feb;6(2):532-41.

Duttaroy A,Voelker F, Zhang X, et al, “The DPP-4 inhibitor vildagliptin increases beta-cell mass in rodents”, Diabetologia (2005);48(suppl 1): p.A178.

Kellar, RS, Shepherd, BR, Larson, DF, Naughton, GK, and Williams, SK. Cardiac Patch Constructed from Human Fibroblasts Attenuates Reduction in Cardiac Function after Acute Infarct. Tissue Engineering, 11(11/12):1678-1687. 2005.

Germann PG, Morawietz G, Krinke G, Maier P, Allmann-Iselin I, Voelker F and Spaet R.  European Society of Toxicologic Pathology Toxicopathology Case Collection. ISBN 3-9522681-0-0. 2003.

Kellar, RS, Kleinert, LB, Williams, SK. Characterization of Angiogenesis and Inflammation Surrounding ePTFE Implanted on the Epicardium. Journal of Biomedical Materials Research. 61 (2): 226-233. 2002.

Roberts, C, Ratcliffe, A, Mansbridge, J , Kellar, RS. Tissue Engineering for Tissue and Organ Repair: Angiogenesis as a Mechanism of Action. Recent Research Developments in Biomaterials. 323-334. 2002.

Germann PG, Voelker FA, Cockerell G, Burkhardt JE, Ryan AM. Importance and impact of discovery pathology.  Exp Toxicol Pathol. 2002 Aug;54(2):165-7

Kidd, KR, Dal Ponte, D, Kellar, RS, Williams, SK. A Comparative Evaluation of Porous Material Implant Healing in the Rat and Mouse.” Journal of Biomedical Materials Research. 59 (4): 682-689. 2002.

Kellar, RS, Landeen, L, Shepherd, BR, Ratcliffe, A, Naughton, G, Williams, SK. Scaffold-Based, Three-Dimensional Human Fibroblast Culture Provides a Structural Matrix That Supports Angigogenesis in Ischemic Heart Tissue. Circulation. 104:2063-2068. 2001.

Raengsakulrach, B., Nisalak, A., Gettayacamin, M., thirawuth, W., Young, G.D., Myint, K.S.A., Ferguson, L.M., Hoke, C.H., Innis, B.L., Vaughn, D.W. Safety, immunogenicity, and protective efficacy of NYVAC-JEV and ALVAC-JEV recombinant Japanese encephalitis vaccines in rhesus monkeys. American Journal of Tropical Medicine and Hygiene. 60(2), 1999.

Myint, K.S.A., Raengsakulrach, B., Young, G.D., Gettayacamin, M., Ferguson, L.M., Innis, B.L., Hoke, C.H., Vaughn, D.W.  Production of lethal infection that resembles fatal human disease by intranasal inoculation of macaques with Japanese encephalitis virus. American Journal of Tropical Medicine and Hygiene 60(2). 1999.

Nisalak, A., Gettayacamin, M., Young, G.D., Myint, K.S.A., Ferguson, L.M., Hoke, C.H., Innis, B.L., Vaughn, D.W.  An intranasal challenge model for testing Japanese encephalitis vaccines in rhesus monkeys.  Raengsakulrach, B. American Journal of Tropical Medicine and Hygiene 60(2). 1999.

Irwin RD, French JE, Elwell M, Haseman J, Braun AG, Voelker FA. Carcinogenicity of dermally administered 1,2-dihydro-2,2,4-trimethylquinoline monomer in F344 rats and B6C3F1 mice. J Appl Toxicol. 1999 Mar-Apr;19(2):125-32.

Petras, J.M., Kyle, D.E., Ngampochjana, M., Young, G.D., Bauman, H.K., Corcoran, K.D., Peggins, J.O., Vane, M.A., Brewer, T.G. Arteether:  Risks of two-week Administration in Macaca mulatta.  Am. J. Trop. Med. Hyg., 56(4): 390-396. 1997.

Tachykinins and Pulmonary Edema Following Acute Phosgene Exposure in Guinea Pigs.  Bauer, R.M., Young, G.D., Keeler, J.R.; Journal of The American College of Toxicology.1996, 15(S2):S99-S112. 1996.

Anderson, D., Yourick, J.J., Moeller, R.B., Petrali, J.P., Young, G.D., Byers, S.L. Pathologic Changes in Rat Lungs Following Acute Sulfer Mustard Inhalation. Inhalation Tox 8:285-297, 1996.

Maneerat, Y., Clayson, E.T., Young, G.D., Innis, B.L. Experimental Infection of the Laboratory Rat with the Hepatitis E Virus.  J.Med.Virol. 48(2):121-128. 1996

Asher, L.V.S., Binn, L.N., Mensing, T.L., Marchwicki, R.H., Vassell, R.A. and Young, G.D; Pathogenesis of Hepatitis A in Orally Inoculated Owl Monkeys (Aotus trivirgatus).  J Med Viro 47:260-268, 1995.

Young, G.D., Koplovitz, I. Acute Toxicity of Cyclohexylmethylphosphonofluoridate (CMPF) in Rhesus Monkeys: Serum Biochemical and Hematologic Changes. Arch Toxicol 69:379-383, 1995.

Franz, D.L., Baze, W.B., Young, G.D., Lewis, G.A. Animal Model of Human Disease: Falciparum Malaria. Comparative Pathology Bulletin, Vol XXII, No 1, 1990.

Krishnamurti, C., Young, G.D., Barr, C.F., Alving, B.A  Comparison of the Efficacy of Tissue Plasminogen A (tPA) and Activated Protein C in Prevention of Thrombi in vivo. Blood 74:368A, 1989.

Frost, D.F., Zaucha, G.M., Young, G.D., Korte, D.W. Acute Intravenous Toxicity Study of Hypertonic Saline/Dextran 70 and Constituents in ICR Mice. Letter Army Institute of Research (LAIR), Institute Report No. 333, LAIR, 1988.

Zaucha, G.M., Frost, D.F., Young, G.D., Korte, D.W. Local Irritation Toxicity Study of Hypertonic Saline/Dextran 70 and Constituents in New Zealand White Rabbits. Letter Army Institute of Research (LAIR), Institute Report No. 332, LAIR, 1988.

Johnson, S.H., Young, G.D., Graeber, G.M. Aortic Replacement and Spinal Cord Ischemia in Swine. Chest 94(l):46S, 1988.

Ameoloblastic Odontoma in a Cynomolgus Monkey.  Davis, J., Banks, R., Young, D.; Lab Ani. Sci. 38:312‑315, 1988.

Montgomery CA, Kari F, Voelker F, Murthy ASK:  Pathology of the repeated dose toxicity of salicylazosulphapyridine in Fischer 344 rats.  Toxicologist 7:  137, 1987.

Franz, D.R., Lee, M., Seng, L.T., Young, G.D., Baze, W.B., Lewis, G.E. Peripheral Vascular Pathophysiology of Plasmodium berghei Infection: A Comparative Study in the Cheek Pouch and Brain of the Golden Hamster. Am. J. Trop. Med. Hyg. 36:474‑480. 1987

Krishnamurti, C., Barr, C.F., Hassett, M.A., Young, G.D., Alving, B.M. Plasminogen Activator Inhibitor: A physiologic Regulator of Ancrod‑Induced Fibrin Deposition in Rabbits. Blood 69:798‑803, 1987.

Walker DH, Voelker FA, McKee AE Jr, Nakano JH. Diagnostic exercise: tumors in a baboon. Lab Anim Sci. 1985 Dec;35(6):627-8.

Vinegar R, Truax JF, Selph JL, Voelker FA. Pathway of onset, development, and decay of carrageenan pleurisy in the rat. Fed Proc. 1982 Jul;41(9):2588-95.

Vinegar R, Truax JF, Selph JL, Johnston PR, Venable AL, Voelker FA. Development of carrageenan pleurisy in the rat: effects of colchicine on inhibition of cell mobilization. Proc Soc Exp Biol Med. 1981 Oct;168(1):24-32.

Voelker FA, Henderson CM, Macklin AW, Tucker WE. Evaluating the rat inner ear. A technique using scanning electron microscopy. Arch Otolaryngol. 1980 Oct;106(10):613-

Brown FC, Gideon RM, Voelker FA, Castell DO. Muscle function and structure of the esophagus of the baboon (Papio anubis). Am J Vet Res. 1978 Jul;39(7):1209-11.

Voelker FA, Kassel SH, Weinberg HD, McKee AE. Microscopic and ultrastructural characteristics of Kudoa infection in a butterfly fish (Chaetodon). Vet Pathol. 15(1):40-8. 1978.

Voelker FA, Anver MR, McKee AE, Casey HW, Brenniman GR. Amebiasis in goldfish. Vet Pathol. 1977 May;14(3):247-55.

Pavlovskis OR, Voelker FA, Shackelford AH. Pseudomonas aeruginosa exotoxin in mice: histopathology and serum enzyme changes. J Infect Dis. 1976 Mar;133(3):253-9.

Migaki G, Voelker FA, Sagartz J:  Mycotic Diseases in Pathology of Laboratory Animals. Vol. II.  Springer Verlag Publishers, New York, Chapter 16, pp. 151-176, 1976.

Voelker FA, Stedham MA, Robinson FR, Casey HW. Glossitis of military working dogs in south Vietnam; histopathologic observations. Am J Vet Res. 1975 May;36(5):683-7.

Voelker FA, Robinson FR, Casey HJ:  Syllabus:  Diseases of the Skin of the Dog.  Armed Forces Institute of Pathology.  1974.

Voelker FA Garner FM:  Case for diagnosis.  Military Medicine.  137: 358, 1972.

Schwetz BA, O’Neil PV, Voelker FA, Jacobs DW. Effects of diphenylthiocarbazone and diethyldithiocarbamate on the excretion of thallium by rats. Toxicol Appl Pharmacol. 1967 Jan;10(1):79-88.