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New approach to angiogenesis

New digital pathology approach to angiogenesis
March 01, 2011
by Steve
0 Comment
analysis approaches, angiogenesis, digital pathology, image analysis techniques, microvessel, tumor tissue, vascular access, vascular analysis, vascularization, vessel walls

Measuring ocular toxicologic changes with pattern recognition

The eye serves as an important organ for toxicology research. Below is a rodent H&E ocular cross-section, followed by pathologist-trained pattern recognition of each layer. This provides a larger and faster region of interest drawing than would be used with manual ROI drawing by a
May 03, 2010
by Frank
0 Comment
angiogenesis, histology pattern recognition, ophthalmology, vascularization

Directed random sampling in pathology

There are  many times when a pathologist needs to randomly sample tissue in a directed manner.  This is to assure that similar tissue substructures are sampled in a manner that prevents biasing of results.  If the problem was as straightforward as sampling ANY area, then random sampli
January 20, 2010
by Frank
1 Comment
angiogenesis, Aperio, biostatistics, digital pathology, directed random sampling, histology pattern recognition, IHC, image analysis, ImageScope, liver, toxicology

Revascularization measurements in a cardiac patch

A scaffold-based, three-dimensional, human dermal fibroblast culture (3DFC) was used as a cardiac patcha to stimulate revascularization and preserve left ventricular (LV) function of the infarcted LV in severe combined immunodeficient (SCID) mice. The histopathology image above illust
January 07, 2010
by Rob
0 Comment
angiogenesis, cardiology, heart, medical devices, microvessel, vascularization

Fibrous capsule measurement for coated devices

Analysis of fibrous capsules is a common procedure in evaluation of coated devices.  Microvessel analysis was tested for use in identifying the fibrous capsule differences between a novel coating and a control polypropylene in a subcutaneous rodent implant model.     Microve
January 07, 2010
by Rob
1 Comment
angiogenesis, biocompatibility, fibrous capsule, medical devices, microvessel
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