Macrophage Biomarkers CD68 and CD163 Correlate with NSCLC Patient Survival (Poster No. 1720 at #AACR2022)

Key Takeaways

  • Image analysis is able to use immune biomarkers to correlate immune cell presence and localization with patient survival in NSCLC.
  • Patient survival correlates with the presence or absence of CD68 and CD163 macrophage markers, but these markers do not match with traditional M1 (anti-tumor) or M2 (pro-tumor) phenotypes.
  • The use of image analysis technology can identify new biomarkers for better characterization of complex immune cell phenotypes.