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POSTERS & PUBLICATIONS

Characterizing the Heterogeneity of CD8 Inflammation in Biopsied Tumor Tissues Using Novel Image Analysis Techniques (Poster No. 3137 #AACR2021 in partnership with Scholar Rock)

Key takeaways An image analysis-based algorithm was used to assess CD8 expression in numerous tumor nests in non-small cell lung cancer, bladder, and melanoma tumor

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April 8, 2021

A Novel Image Analysis Assay for Determining Programmed Death-Ligand (PD-L1 [22C3]) in Non-small Cell Lung Cancer that Accounts for Tissue and Alveolar Macrophages (Poster No. 435 #AACR2021)

Background The Dako PD-L1 (22C3) antibody is used to measure tumor PD-L1 levels in non-small cell lung cancer (NSCLC), serving as a companion diagnostic to

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April 8, 2021

Impact of adding Viagenpumatucel-L (HS-110) to Nivolumab in Non-Small Cell Lung Cancer (NSCLC) Patients with Low Levels of Tumor Infiltrating Lymphocytes

Summary View a scientific, collaborative success with our client, Heat Biologics, presented at the European Society for Medical Oncology (ESMO) Virtual Congress 2020 medical oncology

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September 28, 2020

Image Analysis-Based Identification and Quantification of Macrophages in PD-L1 (22C3) Stained NSCLC Tissue Sections Without Additional Macrophage-Specific Staining

ABSTRACT PD-L1 positivity in tumor-associated macrophages has been related to a favorable response to anti-PD-1 and PD-L1 targeted therapies. This concept has driven interest in

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July 3, 2020

Protein Tyrosine Kinase 7 (PTK7) Biomarker Analysis in Patients treated with PF-06647020, a PTK7 Antibody-Drug Conjugate (ADC), in a Phase I Dose Expansion Study

BACKGROUND F-06647020, an ADC comprising a humanized monoclonal antibody against PTK7, a cleavable valine-citrulline linker, and an auristatin payload, is being investigated in an ongoing

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December 17, 2019

Comprehensive Image Analysis Of Immunostained NSCLC Tissues Provides Necessary Context For Immune Oncology Biomarker Profiling

Key Takeaways Manual pathology assessment is challenging and variable, limiting the data interpretation required for meaningful spatial biology analysis Unlike manual assessment, artificial intelligence and

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November 11, 2019
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    Flagship carefully tracks our tissue to ensure we can analyze every assay and stay on schedule.
    Sr. Pharmaceutical Research Director
    Sr. Pharmaceutical Research Director
    We are trying to bridge from the discovery stage to clinical development. Flagship's pathologists and scientists provide critical input and the company helps us organize and analyze an incredible amount of data. I highly recommend Flagship for its expertise and support for drug development projects.
    Biopharma Director
    Biopharma Director
    During clinical trials, I interact with our manufacturing, legal, pre-clinical, and biomarker teams. Our Flagship project manager understands our tight timeline and ensures delivery of the data we need, when we need it.
    Biotech Pharmaceutical Operations Director
    Biotech Pharmaceutical Operations Director
    We are pleased to partner with Flagship Biosciences to integrate their machine learning/AI tools to provide cancer marker detection.
    Laboratory Software Solutions Provider COO
    Flagship’s image analysis experts are flexible and willing to work with us to develop projects that meet the changing needs of our clinical trials drug development.
    Sr. Pharmaceutical Research Director
    Flagship has a high reputation as a supplier of advanced IHC services and their CAP-CLIA environment is a perfect complement to our own testing facilities.
    Global Oncology Research Database Provider CEO
    The ease of leveraging Flagship’s powerful solution is yet another massive differentiator of the company. Clients need not have to change their existing workflows, investments in technology, or even the assays that they use.
    CIO Review, Pharma and Life Sciences

    About Flagship Biosciences

    We are a multi-disciplinary team of pathologists, biologists, analysts, software engineers, and technicians who are committed to creating successful approaches which match patients with life-saving drugs.
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