Digital Spatial Profiling (DSP) using the NanoString GeoMx® platform offers a powerful, high-resolution approach to understanding biomarker expression in the spatial context of tissue architecture. By combining multiplexed RNA or protein quantification with precise spatial localization, DSP enables researchers to uncover critical insights into the tumor microenvironment, immune infiltration, and cellular heterogeneity—without disrupting tissue morphology. Our team of scientific experts works collaboratively with clients to design region-of-interest (ROI) strategies tailored to their study goals, whether targeting tumor, stroma, immune compartments, or areas defined by pathology or prior IHC. With proven experience in oncology, immunology, and translational research, we offer end-to-end support from sample prep and ROI selection to data interpretation and integration with complementary modalities such as IHC, mIF, and qPCR. Flagship’s DSP services provide the clarity and depth needed to drive biomarker discovery, patient stratification, and mechanism-of-action studies with confidence.

Digital Spatial Profiling (DSP) using the NanoString GeoMx® platform offers a powerful, high-resolution approach to understanding biomarker expression in the spatial context of tissue architecture. By combining multiplexed RNA or protein quantification with precise spatial localization, DSP enables researchers to uncover critical insights into the tumor microenvironment, immune infiltration, and cellular heterogeneity—without disrupting tissue morphology. Our team of scientific experts works collaboratively with clients to design region-of-interest (ROI) strategies tailored to their study goals, whether targeting tumor, stroma, immune compartments, or areas defined by pathology or prior IHC. With proven experience in oncology, immunology, and translational research, we offer end-to-end support from sample prep and ROI selection to data interpretation and integration with complementary modalities such as IHC, mIF, and qPCR. Flagship’s DSP services provide the clarity and depth needed to drive biomarker discovery, patient stratification, and mechanism-of-action studies with confidence.