Analysis of Multiplexed Immunotherapy Targets and Secreted Ligands Using Computational Tumor Microenvironment Profiling

Key takeaways

  • The RNAscope® platform enabled duplex chromogenic in situ hybridization (CISH) assay visualization of mRNA targets from multiple cell types and biomarkers
  • Quantification of individual and dual cell positivity within tissue compartments
  • Spatial biology assessment revealed relationships between cell types and biomarkers

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